Easier to install, modern controls, and updated graphics.
GTA San Andreas is intellectual property of Take-Two Interactive. Downloading it without payment via MediaFire is piracy. ISPs can flag your activity, and fines for digital piracy can range from $750 to $30,000 per work under the Copyright Act.
Portable versions are often less invasive but still require a valid game license.
This version updated the graphics and controls in 2021. Because it is a paid product, any "free" download on a file-sharing site is a cracked version, which carries risks of malware or incomplete files.