Ensure your GPU drivers are current via the NVIDIA GeForce Experience or AMD Software.
Based on 100+ player reports, the are:
The House of the Dead: Remake is a "Fix It Yourself" project. Out of the box, the PC port is unstable and frustrating. However, if you are willing to spend 15 minutes tweaking settings and following community guides, the game is perfectly playable and a worthy addition to a rail shooter fan's library. house of the dead remake crash fix